Ipamorelin is a growth hormone–releasing peptide (GHRP) designed to gently stimulate your body’s own growth hormone (GH) pulses, rather than replacing hormones from the outside.

It works by activating the ghrelin (GHS-R1a) receptors in the brain and pituitary gland. These receptors are part of the natural signalling system that tells your body to release growth hormone in short pulses, supports repair, recovery, and tissue renewal while having an influence on metabolism and body composition. 

Ipamorelin is often described as a “clean” GH secretagogue because, compared to older peptides in the same family, it has minimal impact on cortisol and prolactin (stress-related hormones), A lower tendency to cause intense hunger than traditional GHRPs, and a more targeted action on GH release

IPAMORELIN is not an FDA-approved anti-ageing or weight-loss drug. Use is based on emerging evidence and clinical experience and must always be supervised by a qualified clinician, alongside nutrition, training, sleep and stress management.

When used as directed and alongside a healthy lifestyle, clients commonly use Ipamorelin to help support:

Deeper, more restorative sleep

Growth hormone naturally peaks during deep sleep. By supporting these pulses, Ipamorelin is often used to promote better-quality sleep and improved “next day” energy.

Recovery from training & busy schedules

GH, and the downstream IGF-1 it produces, are central to tissue repair. Ipamorelin can be used to help the body recover from gym sessions, physical work and general life stress.

Lean muscle support & body composition

In combination with a structured resistance-training plan and adequate protein intake, Ipamorelin is used to support lean mass and body recomposition.

Fat metabolism & metabolic health

GH-releasing protocols are frequently used in fat-loss and recomposition programs to assist with fat mobilisation while trying to protect muscle.

Healthy-ageing & long-term vitality

By nudging your own GH rhythm (rather than flat dosing like synthetic GH), Ipamorelin is often included in healthy-ageing programs focused on performance, tissue quality and resilience.

*Individual results vary. This peptide blend works best as part of a complete plan created with your healthcare provider and is not a substitute for healthy nutrition, movement, sleep or medical care.

Active Ingredient

Ipamorelin – 2,000 mcg/mL

Excipients

Sterile diluent (e.g., bacteriostatic saline) and standard compounding excipients as specified by the partner pharmacy (may include buffering agents and preservatives).

Presentation 

Injectable

2000 mcg/mL Ipamorelin, 5 mL multidose vial
Total peptide content per vial: 10,000 mcg at 2,000 mcg/mL

Cream & Forte Cream

Ipamorelin Cream: 200 mcg per mL
Ipamorelin Forte Cream: 400 mcg per mL
Bottle volume – 100ml

Protocol & Standard Dosing

Injectable – Ipamorelin 2000 mcg/mL, 5 mL Vial

Body-weight–based standard dosing
< 70 kg: 0.10 mL SC nightly on an empty stomach, 5 days per week (5/7)
> 70 kg: 0.15 mL SC nightly on an empty stomach, 5 days per week (5/7)

Potential dose increase (if tolerated and indicated)

0.10 mL twice daily in smaller individuals
0.15 mL twice daily in larger individuals
Only under prescriber guidance and if well tolerated.

Timing & administration

Inject last thing before bed, at least 2 hours after the last meal.

Route:

Subcutaneous injection into fatty tissue (e.g. lower abdomen, outer thigh) using a fine insulin syringe, as taught by a healthcare professional.
Typical schedule: 5 days on / 2 days off each week (e.g. Mon–Fri on, weekend off).

Cream & Forte Cream – 200 mcg & 400 mcg per mL
Dose:

1 mL (2 pumps)

Application site:

Transdermal to inner forearms (or as directed)

Timing:

Nightly or AM post-shower on an empty stomach
Frequency: 5 days per week (5/7)

Potential dose increase

May increase to twice daily application (e.g. morning and night) if tolerated and clinically indicated, under prescriber guidance.

How to use (topical)

1. Apply to clean, dry skin on the inner forearms.
2. Rub in thoroughly and allow to dry before dressing.
3. Wash hands after application and avoid transferring product to others through direct skin contact at the application site until absorbed.

Side Effects, Reactions & Medical Contraindications

Use is generally not recommended in:

• Known allergy or hypersensitivity to Ipamorelin or any component of the vial/cream base
• Pregnancy or breastfeeding (insufficient safety data)
• Active malignancy or history of cancer unless cleared by a specialist (due to theoretical effects on growth pathways)
• Uncontrolled diabetes, significant cardiovascular disease, severe kidney or liver disease without specialist supervision
• History of intracranial tumours or pituitary disorders unless managed by a specialist
• Individuals subject to professional or federation anti-doping testing (WADA or similar), as GH secretagogues are generally prohibited in tested sport

Common Side Effects and Adverse Reactions – Often mild and transient where they occur:

Injectable

• Injection-site redness, itching, mild swelling or small bruises
• Mild water retention or puffiness
• Changes in sleep pattern (vivid dreams, deeper sleep, altered sleep onset)
• Headache, light-headedness or fatigue, especially in the first 1–2 weeks
• Mild increase in hunger or appetite (less pronounced than older GHRPs, but still possible)

Topical Cream / Forte

• Local skin irritation at the application site (redness, itching, dryness or slight burning)
• Occasional transient flushing or warmth
• Rarely, mild systemic effects similar to low-dose injectable use (e.g. vivid dreams, mild headache)
• If any of these symptoms are persistent, uncomfortable or worrying, contact your healthcare provider to review dose, timing or whether to pause treatment.

Reactions Requiring Medical Attention

Stop treatment and contact a healthcare provider (or emergency services if severe) if experiencing:

• Signs of a serious allergic reaction:
• Widespread rash or hives
• Facial, lip or tongue swelling
• Difficulty breathing or swallowing
• Severe or persistent headache, visual changes, chest pain or shortness of breath
• Marked swelling of ankles/hands, rapid unexplained weight gain, or significant changes in blood pressure
• Any new or rapidly worsening symptom that feels serious, unusual or concerning

Safety Note: Long‑term data is limited. Use should always be monitored by a qualified clinician, with regular reviews and ongoing medical supervision.  Informed consent is essential.