SARMS S-22 is a selective androgen receptor modulator–style (SARM-like) peptide designed to support lean muscle, strength and performance under professional supervision.

SARMS S-22 may treat anabolic resistance, the reduction in the body's response to normal anabolic signalling.

Androgens (like testosterone) are the body’s “build and power” hormones. They work by binding to androgen receptors in cells, which then tell the body to build more muscle fiber, strengthen bone, Influence energy, drive and recover.

Traditional anabolic hormones hit androgen receptors everywhere - muscle, bone, prostate, skin, scalp  - which is why they can be powerful but also come with a higher risk of side effects.

S-22 is designed to be more selective. That means it aims to preferentially activate androgen receptors in muscle and bone while having less activity in tissues such as the prostate and scalp that are associated with many unwanted androgenic side effects.

What does that actually mean in the body?

When S-22 binds to androgen receptors in muscle tissue it sends a message to turn on muscle-building genes, Supports protein synthesis, muscle fibre repair and growth.

S22 may help muscle cells hold onto nitrogen and nutrients more effectively and over time (with training and the right diet), this can translate into better strength, power and lean mass

In bone tissue, selective androgen signalling can support better bone density and integrity, stronger structural support for lifting, impact and daily movement.

Because S-22 is taken in a structured, repeated fashion (rather than as a single “pre-workout hit”), it acts as a background anabolic signal: “stay strong, stay recovered, stay building” – but it still relies on you doing the work:

We offer S-22 in multiple delivery formats:

Standard injectable vials (2000 mcg/mL) for predictable, consistent dosing

Forte injectable vials (3000 mcg/mL) with higher concentration for smaller injection volumes

Transdermal cream (1000 mcg/mL) for a non-injectable option

SARMS S22 is not an FDA‑approved medicine and is not intended to diagnose, treat, cure or prevent any disease. Always follow the advice of your prescribing practitioner.

When used exactly as directed and alongside structured training and nutrition, clients commonly use SARMS S-22 to help support:

Lean muscle gain & strength

More support for muscle tissue so that hard work in the gym translates into better strength and size over time.

Performance & training quality

Helping athletes and active people push harder, recover better and show up more consistently to their sessions.

Muscle protection during fat-loss phases

When calories are reduced, S-22 may be used (under supervision) to help protect lean mass and “hold onto” strength while body fat is targeted.

Structural & functional support in healthy ageing

A focus on maintaining strong, functional muscle and capacity not just how the body looks as part of longevity and vitality programs.

*Individual results vary. This peptide blend works best as part of a complete plan created with your healthcare provider and is not a substitute for healthy nutrition, movement, sleep or medical care.

Active Ingredients

Injectable – Standard (2000 mcg/mL)

Available vial sizes:

• 2000 mcg/mL, 5 mL multidose vial
  Total peptide content: 10,000 mcg
• 2000 mcg/mL, 10 mL multidose vial
  Total peptide content: 20,000 mcg
• 2000 mcg/mL, 20 mL multidose vial
  Total peptide content: 40,000 mcg

Injectable – Forte (3000 mcg/mL)

Available vial sizes:

• 3000 mcg/mL, 5 mL multidose vial
  Total peptide content: 15,000 mcg
• 3000 mcg/mL, 10 mL multidose vial
  Total peptide content: 30,000 mcg
• 3000 mcg/mL, 20 mL multidose vial
  Total peptide content: 60,000 mcg

Transdermal Cream

Strength

1,000 mcg/mL

Presentation

100 mL pump bottle

Total peptide content: 100,000 mcg

Protocol & Standard Dosing

Injectable SARM S-22 (Standard & Forte Vials) 2000 mcg/mL or 3000 mcg/mL vials

Standard Dose

0.25 mL subcutaneous (SC)

Post-training, 5 days per week (5/7)

This applies to both Standard and Forte; Forte simply delivers more peptide per 0.25 mL and is usually chosen where higher potency per injection is desired, as directed by the prescriber.

Timing

Inject after training on training days (or same approximate time on non-training days if still dosing 5/7).

Route & Administration

Subcutaneous injection using a fine insulin syringe.

Inject into fatty tissue (e.g. lower abdomen or outer thigh), rotating injection sites and using aseptic technique.

Transdermal SARM S-22 Cream

1 mL cream per application

(e.g. 2 pumps if your pump dispenses 0.5 mL per pump – confirm on your label.)

Application Site

Apply to clean, dry skin – e.g. inner arms, abdomen, thighs or shoulders, as directed by your clinician.

Timing & Frequency

• Typically once daily, ideally post-training or at the same time each day, 5 days per week (5/7).
• Allow the cream to absorb fully before dressing.
• Wash hands thoroughly after application and avoid transferring product to others’ skin until fully absorbed.

Side Effects, Reactions & Medical Contraindications

Use is generally not recommended in:

• Known allergy or hypersensitivity to S-22 or any component of the vial/cream
• Pregnancy or breastfeeding (contraindicated)
• Individuals under 18 years of age
• History of hormone-sensitive cancers (e.g. prostate, breast) unless explicitly cleared and monitored by a specialist
• Significant untreated prostate disease in men
• Uncontrolled cardiovascular disease, significant hypertension, history of stroke or thromboembolic events without specialist oversight
• Severe liver or kidney disease without specialist supervision
• Individuals at high risk for, or with a history of, severe mood disorders or aggression, without appropriate monitoring
• Anyone subject to professional or federation anti-doping testing (WADA / similar) – SARMs are banned substances in tested sport
• Always disclose your full medical history and all medications/supplements to your clinician before starting S-22.

Common Side Effects and Adverse Reactions – Often dose-related and more likely at higher/intensive protocols:

Injectable

• Injection-site reactions: redness, itching, mild swelling or bruising

Cream

• Local skin irritation: redness, itching, dryness or mild rash
• Systemic / Hormone-like effects
• Changes in libido
• Mild acne or oily skin
• Possible hair shedding/thinning in genetically susceptible men
• Mood shifts (feeling more driven or occasionally more irritable)
• Mild fluid retention or changes in blood pressure in some individuals
• If side effects are persistent, uncomfortable or worrying, contact your healthcare provider for review and possible dose adjustment or discontinuation.

Reactions Requiring Medical Attention – Stop using S-22 and seek medical care (or emergency services if severe) if you experience:

Signs of a serious allergic reaction:

• Widespread rash or hives

• Swelling of the face, lips or tongue
• Difficulty breathing or swallowing
• Serious hormonal or cardiovascular symptoms:
• Chest pain, marked shortness of breath, palpitations
• Sudden, severe headache, visual changes, weakness or numbness
• Rapid unexplained weight gain, significant swelling of ankles or hands, or concerning rise in blood pressure
• Any new or worsening symptom that feels serious, unusual or concerning

Safety Note

• S-22 is an advanced, SARM-like peptide used within optimisation and performance contexts. Important safety points:
• Long-term human data on SARMs and SARM-like compounds are limited.
• Use should always be clinician-prescribed and closely monitored, including periodic blood tests (lipids, liver function, hormones, glucose, blood pressure, etc.) as appropriate.
• It should be positioned as adjunctive support, not a replacement for proper training, nutrition, recovery or medically indicated hormone therapy.
• It is not appropriate for tested athletes and may have legal/regulatory implications depending on jurisdiction.

Safety Note: Long‑term data is limited. Use should always be monitored by a qualified clinician, with regular reviews and ongoing medical supervision.  Informed consent is essential.