This Acetyl Hexa Peptide 5% Serum is a concentrated cosmeceutical formula designed to visibly soften the look of fine lines and expression wrinkles, especially around areas that move a lot, like the eyes, forehead and smile lines. Acetyl hexapeptide is often described as a “peptide-based expression relaxer” because it works at the level of the skin–nerve interface, helping to reduce the visible impact of repeated muscle movement on the skin’s surface. Over time, the repetitive creasing from smiling, frowning and squinting can etch lines into the skin; this peptide is used to help the skin look smoother, more rested and more refreshed, without freezing expression.

The serum is formulated in a lightweight, fast-absorbing base so it can be layered easily under moisturiser, SPF or makeup and fit seamlessly into both morning and evening routines. With consistent use, many people notice that the skin around key expression zones looks more supple, hydrated and plump, and that make-up sits more evenly over time. It is ideal for clients who want a high-performance, clinic-grade active that supports an ageing-gracefully approach, either as a stand-alone cosmetic product or alongside in-clinic treatments such as needling, light therapies or injectables as advised by their practitioner.

This is a topical skincare product, not an injectable or prescription treatment. Results build gradually with regular use and are best supported by a full routine that also includes broad-spectrum sunscreen, barrier-supporting moisturisers and healthy lifestyle foundations.

When used consistently as part of a regular skincare routine, clients commonly use Acetyl Hexa Peptide 5% Serum to help support:

Softer appearance of expression lines

Used around the eyes, forehead and smile lines to help the skin look smoother and more relaxed where repeated movement has etched in fine lines.

Smoother skin texture

Supports a more refined surface appearance so that skin looks more even and makeup applies more smoothly.

Improved skin suppleness and bounce

Regular use can help the skin feel more elastic and “springy”, contributing to an overall more youthful look.

Refreshed, less “tired” appearance

By softening harsh lines and supporting hydration, the face can look more rested and relaxed, particularly around the eye area.

Support alongside in-clinic treatments

Often used as a home-care complement to professional treatments, helping to maintain and enhance clinic results when recommended by a practitioner.

*Individual results vary. This serum is a cosmetic skincare product and does not replace medical treatments or procedures.

Key Active Ingredient

Acetyl Hexa Peptide – 5% (high-strength cosmetic peptide complex)

Presentation

• Serum
• 5% acetyl hexa peptide concentration
• 10 mL pump bottle
• 20 mL pump bottle

Protocol & Standard Dosing

Skin Type

Suitable for most skin types, including normal, combination and mature skin.

Can be used on sensitive skin if tolerated; patch testing is recommended for reactive clients.

Standard Use

Application amount:

1–2 small pumps or 2–3 drops, depending on bottle format.

Areas:

Focus on expression-prone zones – crow’s feet, under and outer eye area (avoiding direct contact with eyes), forehead lines, frown lines and smile lines around the mouth.

Step-by-step

1. Cleanse the skin and gently pat dry.
2. Apply a small amount of Acetyl Hexa Peptide 5% Serum to targeted areas or the full face, avoiding direct eye contact.
3. Allow to absorb fully.
4. Follow with your usual moisturiser and, in the morning, a broad-spectrum SPF 30+ or 50+.

Frequency

AM and/or PM use

Most clients will use it twice daily for more intensive support, or once daily for maintenance, as advised by their practitioner.

Results are gradual and typically require consistent use over several weeks as part of a broader skincare routine.

Side Effects, Reactions & Medical Contraindications

Use is generally not recommended in:

• Individuals with a known allergy or sensitivity to any ingredient in the serum.
• Broken, infected or severely irritated skin in the intended application area.
• Those who have recently undergone resurfacing procedures (e.g. deep peels, ablative lasers) unless cleared by their treating practitioner.
• Pregnant and breastfeeding individuals can usually use topical cosmetic peptides, but should always check with their healthcare provider if unsure and review the full ingredient list.

Possible Side Effects

• Most people tolerate acetyl hexa peptide serums well. Where side effects occur, they are usually mild and may include:
• Temporary redness, tingling or mild irritation at the application site.
• Dryness or tightness if used with multiple strong actives (e.g. retinoids, acids) without adequate moisturiser.
• If significant irritation, rash, swelling, stinging or discomfort occurs, clients should stop use and consult their skincare professional or healthcare provider.

Safety & Use Notes

• For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water.
• Always perform a patch test on a small area behind the ear or along the jawline 24 hours before first full use, especially in sensitive or reactive skin.
• Store in a cool, dry place away from direct sunlight. Keep the cap tightly closed to protect peptide stability.
• This product is a cosmetic skincare serum, not a prescription medicine or injectable; it is designed to support the visible appearance of skin, not treat medical conditions.