This HCG protocol is designed for people who want targeted, medically supervised support during a focused fat-loss phase. It uses low-dose human chorionic gonadotropin (hCG), a hormone that talks directly to your body’s hormone and fat-storage systems, to help you get more out of a well-structured weight-loss plan.

HCG sends signals through the same receptors involved in reproductive and steroid hormone production. In selected individuals, this can help support a more favourable hormonal environment for fat loss by encouraging the body to mobilise stored fat as an energy source during a calorie-controlled plan.

HCG can help to protect lean muscle, so more of the weight you lose comes from fat rather than hard-earned muscle tissue, while supporting testosterone and related hormone pathways in appropriate patients, which are closely tied to metabolism, energy and motivation.

HCG for weight loss is an off-label use and must only be done under the care of an experienced clinician. Your practitioner will assess your health, goals and lab results, then decide if this protocol is appropriate and safe for you, and will monitor your progress throughout the program.

When used exactly as directed and as part of a structured program, clients commonly use this HCG protocol to help support:

Adherence to a weight-loss plan

Being under medical supervision with a defined protocol may help patients stay committed to their nutrition and lifestyle targets during an intensive fat-loss phase.

Muscle and metabolic support while dieting

When paired with adequate protein and resistance training, the goal is to support lean tissue and metabolic rate while body fat is being reduced.

Energy, mood and motivation during a calorie deficit

A guided, hormone-informed approach can help some clients feel more supported through the ups and downs of a focused weight-loss phase.

Structured, time-bound fat-loss phases

Clear start and end dates (e.g. 21-day cycles) can help patients mentally “chunk” their transformation into manageable blocks within a longer-term health plan.

*Individual results vary. HCG is not a magic weight-loss solution and will not override a poor diet or sedentary lifestyle. It must always be part of a supervised, evidence-based protocol that prioritises safety and long-term health.

Presentation

HCG 1,000 IU/mL, 5 mL multidose vial

Total peptide content: 5,000 IU per vial (at 1,000 IU/mL)

Excipients

Sterile diluent (e.g., bacteriostatic saline) and standard compounding excipients as specified by the partner pharmacy (may include buffering agents and preservatives).

Protocol & Standard Dosing

Subcutaneous injection into fatty tissue (e.g., lower abdomen, outer thigh), using an insulin type syringe, as instructed by a healthcare professional.

Standard Dose 

Vial: 0.125 mL subcutaneous (SC) injection (125 IU)

Timing

In the morning upon waking, fasted

Frequency

Daily for 21 days, maximum 42 days followed by at least 6 week break/

Dosing & Administration Instructions

Inject 0.125 mL (12.5 units on a standard 1 ml insulin syringe) via subcutaneous injection every morning:

On waking

On an empty stomach (fasted)

Administer into fatty tissue (e.g. lower abdomen or outer thigh) using an insulin syringe, as instructed by your healthcare practitioner.

Cycle Structure

21-day active phase, followed by a transition / maintenance phase as directed by your clinician.

Course length and repeat cycles will depend on your response, goals and safety considerations.

Listed as a prohibited substance in sport (World Anti‑Doping Code); athletes subject to testing should not use this product

Side Effects, Reactions & Medical Contraindications

Use is generally not recommended in:

• Known allergy or hypersensitivity to hCG or any vial component
• Pregnancy (hCG is a pregnancy-related hormone) or breastfeeding
• Hormone-sensitive cancers or history of such cancers (e.g. breast, prostate, endometrial) unless explicitly cleared by a relevant specialist
• Men with untreated prostate enlargement or suspected/active prostate cancer
• Blood clotting disorders
• Uncontrolled significant cardiovascular disease, severe kidney or liver disease, or history of thromboembolic events without specialist oversight
• Individuals with eating disorders, severe psychiatric conditions or unstable mental health, unless closely supervised within a specialist treatment team
• Individuals subject to professional or federation anti-doping testing, as hCG may be prohibited in certain sports and categories

Common Side Effects and Adverse Reactions

Often mild and transient where they occur:

• Injection-site reactions
• Redness, itching, mild swelling or small bruises at the injection site
• Fluid and hormonal shifts
• Mild water retention or puffiness
• Breast tenderness (more common in men on hormone therapy)
• Changes in libido or mood
• Headache, light-headedness or fatigue. Especially early in the protocol or in the context of calorie restriction
• Diet-related symptoms
• Hunger, low energy or irritability if nutrition and hydration are not carefully managed during the program
• If side effects are persistent, uncomfortable or worrying, contact your healthcare provider for review and possible adjustment of the protocol.

Reactions Requiring Medical Attention

Stop injections and contact a healthcare provider (or emergency services if severe) if experiencing:

• Signs of a serious allergic reaction:
• Widespread rash or hives
• Facial, lip or tongue swelling
• Difficulty breathing or swallowing
• Severe hormonal or cardiovascular symptoms, such as:
• Marked breast swelling or pain
• Severe mood swings, aggression, or major changes in mental health
• Chest pain, severe shortness of breath, sudden palpitations
• Calf swelling
• Significant swelling of ankles/hands, rapid unexplained weight gain, or strong rise in blood pressure
• Any new or worsening symptom that feels serious, unusual or concerning

Safety Note

HCG for weight loss is an off-label use and remains controversial in the medical community. Robust evidence that hCG alone causes fat loss beyond that achieved by diet is limited, and regulatory bodies have issued warnings about unapproved hCG weight-loss products.

Because of this, use should only occur:

• Under the care of a qualified clinician who understands your full medical history
• Within a structured, evidence-based weight-loss framework that emphasises nutrition, physical activity, sleep and mental health
• With regular monitoring of symptoms, side effects and (where appropriate) lab markers
• Informed consent is essential, and patients should clearly understand the experimental nature of using hCG specifically for weight-loss support.